Identification and validation of biomarkers for autism spectrum disorders.

Eva Loth (1) , Will Spooren (2) , Lindsay M Ham (3) , Maria B Isaac (4) , Caroline Auriche-Benichou (5) , Tobias Banaschewski (6, 7) , Simon Baron-Cohen (8) , Karl Broich (9) , Sven Bölte (10) , Thomas Bourgeron (11) , Tony Charman (1) , David Collier (12) , Fernando de Andres-Trelles (13) , Sarah Durston (14) , Christine Ecker (1) , Andre Elferink (15) , Marion Haberkamp (9) , Robert Hemmings (4) , Mark H Johnson (16) , Emily Jones (16) , Omar S Khwaja (2) , Sabine Lenton (15) , Luke Mason (16) , Valentina Mantua (17) , Andreas Meyer-Lindenberg (6, 7) , Michael V Lombardo (8, 18) , Laurence O'Dwyer (19) , Koichi Okamoto (2) , Gahan J Pandina (20) , Luca Pani (17) , Antonio M Persico (21) , Emily Simonoff (1) , Sitra Tauscher-Wisniewski (12) , Jordi Llinares-Garcia (4) , Spiros Vamvakas (4) , Steve Williams (1) , Jan K Buitelaar (19) , Declan G M Murphy (1)

1 Institute of Psychiatry, Psychology & Neuroscience, King's College London
2 pRED - Roche Pharma Research and Early Development [Basel]
3 F. Hoffmann-La Roche [Basel]
4 EMA - European Medicines Agency [London]
5 ANSM - Agence nationale de sécurité du médicament et des produits de santé [Saint-Denis]
6 Medizinische Fakultät Mannheim
7 Universität Heidelberg [Heidelberg] = Heidelberg University
8 CAM - University of Cambridge [UK]
9 Federal Institute of Drugs and Medical Devices [Bonn]
10 Karolinska Institutet [Stockholm]
11 GHFC (UMR_3571 / U-Pasteur_1) - Génétique humaine et fonctions cognitives - Human Genetics and Cognitive Functions
12 Eli Lilly and Company Limited [Windlesham]
13 AEMPS - Spanish Medicines Agency and Medical Devices [Madrid]
14 University Medical Center [Utrecht]
15 Medicines Evaluation Board [Utrecht]
16 Centre for Brain and Cognitive Development [Birkbeck College]
17 AIFA - Italian Medicines Agency [Roma]
18 UCY - University of Cyprus [Nicosia]
19 Radboud University Medical Center [Nijmegen]
20 Janssen Research & Development
21 UCBM - Università Campus Bio-Medico di Roma / University Campus Bio-Medico of Rome

Keywords: Gene expression profiling; Autism spectrum disorders; Biomarkers; Brain imaging

Domains: Cognitive science; Life Sciences [q-bio]; Genetics; Psychiatrics and mental health

Eva Loth, Will Spooren, Lindsay M Ham, Maria B Isaac, Caroline Auriche-Benichou, et al.. Identification and validation of biomarkers for autism spectrum disorders.. Nature Reviews Drug Discovery, 2015, 15 (1), pp.70-3. ⟨10.1038/nrd.2015.7⟩. ⟨pasteur-01578120⟩