The difference bidirectionality makes to the kinetic modeling of molecular catalysis

Andrea Fasano (1) , Vincent Fourmond (1) , Christophe Léger (1)

1 BIP - Bioénergétique et Ingénierie des Protéines

The quantitative modeling of voltammograms obtained with molecular redox catalysts is important for mechanistic studies and benchmarking. Most kinetic models developed for that purpose were based on unidirectional reaction mechanisms, but many redox enzymes work in both directions of the reaction, and chemists have recently successfully designed bidirectional, synthetic, molecular catalysts. An important conclusion from recent work is that unidirectional kinetic models should not be used to interpret bidirectional electrochemical responses. Understanding the latter will require much more work than simply adapting unidirectional models.

Mots clés: Electrochemistry; Catalysis; Bidirectionality; Kinetic modeling; Molecular catalysis; Redox enzymes Bidirectionality versus reversibility

Domaines: Catalyse; Chimie théorique et/ou physique

Andrea Fasano, Vincent Fourmond, Christophe Léger. The difference bidirectionality makes to the kinetic modeling of molecular catalysis. Current Opinion in Electrochemistry, 2024, 46, pp.101489. ⟨10.1016/j.coelec.2024.101489⟩. ⟨hal-04550686⟩