Non-Coding RNAs in Renal Fibrosis
Résumé
Fibrosis, or tissue scarring, is defined as the excessive, persistent and destructive accumulation of extracellular matrix components in response to chronic tissue injury. Renal fibrosis represents the final stage of most chronic kidney diseases and contributes to the progressive and irreversible decline in kidney function. The role of non-coding RNAs, and in particular microRNAs (miRNAs), has been described in kidney fibrosis.