Immunological exhaustion: How to make a disparate concept operational?
Résumé
In this essay, we show that 3 distinct approaches to immunological exhaustion coexist and that they only partially overlap, generating potential misunderstandings. Exploring cases ranging from viral infections to cancer, we propose that it is crucial, for experimental and therapeutic purposes, to clarify these approaches and their interconnections so as to make the concept of exhaustion genuinely operational.
Fichier principal
Kaminski-Lemoine-Pradeu_Immunological exhaustion_PLoS Path_Final draft.pdf (907.3 Ko)
Télécharger le fichier
Origine : Fichiers produits par l'(les) auteur(s)