Fungi participate in the dysbiosis of gut microbiota in patients with primary sclerosing cholangitis

Sara Lemoinne (1) , Astrid Kemgang (1) , Karima Ben Belkacem (1) , Marjolene Straube (2, 3) , Sarah Jegou (4) , Christophe Corpechot (1) , Olivier Chazouillères (1) , Chantal Housset (5) , Harry Sokol (2, 3, 6)

1 CHU Saint-Antoine [AP-HP]
2 MICALIS - MICrobiologie de l'ALImentation au Service de la Santé
3 Université Paris Saclay (COmUE)
4 LBM UMR 7203 - Laboratoire des biomolécules
5 CHU Pitié-Salpêtrière [AP-HP]
6 CRSA - Centre de Recherche Saint-Antoine

Patients with primary sclerosing cholangitis (PSC) were previously shown to display a bacterial gut dysbiosis but fungal microbiota has never been examined in these patients. The aim of this study was to assess the fungal gut microbiota in patients with PSC.

Keywords: inflammatory bowel disease; primary sclerosing cholangitis; gut microbiota; fungi

Domains: Life Sciences [q-bio]; Human health and pathology; Hépatology and Gastroenterology

Sara Lemoinne, Astrid Kemgang, Karima Ben Belkacem, Marjolene Straube, Sarah Jegou, et al.. Fungi participate in the dysbiosis of gut microbiota in patients with primary sclerosing cholangitis. Gut, 2019, pp. gutjnl-2018-317791. ⟨10.1136/gutjnl-2018-317791⟩. ⟨hal-02116096⟩