Analysis of interaction between telomeric i-motif DNA and a cyclic tetraoxazole compound
Résumé
The interaction of a macrocyclic tetraoxazole compound, L2H2‐4OTD (1), with two aminoalkyl side chains and telomeric i‐motif, was investigated by means of electrophoretic mobility shift assay, circular dichroism spectroscopy, mass spectrometry and NMR spectroscopy analyses. The results indicate that 1 interacts with the i‐motif structure at two preferred binding sites.
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Manuscript_Nagasawa_accepted.pdf (644.75 Ko)
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Manuscript_Nagasawa_accepted_SI.pdf (1.24 Mo)
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