Skip to Main content Skip to Navigation
Journal articles

Biomolecular hydration dynamics: a jump model perspective

Abstract : The dynamics of water molecules within the hydration shell surrounding a biomolecule can have a crucial influence on its biochemical function. Characterizing their properties and the extent to which they differ from those of bulk water have thus been long-standing questions. Following a tutorial approach, we review the recent advances in this field and the different approaches which have probed the dynamical perturbation experienced by water in the vicinity of proteins or DNA. We discuss the molecular factors causing this perturbation, and describe how they change with temperature. We finally present more biologically relevant cases beyond the dilute aqueous situation. A special focus is on the jump model for water reorientation and hydrogen bond rearrangement.
Document type :
Journal articles
Complete list of metadatas

Cited literature [53 references]  Display  Hide  Download

https://hal.sorbonne-universite.fr/hal-01774658
Contributor : Damien Laage <>
Submitted on : Monday, April 23, 2018 - 6:10:37 PM
Last modification on : Tuesday, December 8, 2020 - 3:34:02 AM
Long-term archiving on: : Wednesday, September 19, 2018 - 3:11:08 AM

File

rsc_v6.pdf
Files produced by the author(s)

Identifiers

Citation

Aoife Fogarty, Elise Duboué-Dijon, Fabio Sterpone, James Hynes, Damien Laage. Biomolecular hydration dynamics: a jump model perspective. Chemical Society Reviews, Royal Society of Chemistry, 2013, 42 (13), ⟨10.1039/C3CS60091B⟩. ⟨hal-01774658⟩

Share

Metrics

Record views

300

Files downloads

781