Crystallization via tubing microfluidics permits both in situ and ex situ X-ray diffraction

Abstract : We used a microfluidic platform to address the problems of obtaining diffraction quality crystals and crystal handling during transfer to the X-ray diffractometer. We optimize crystallization conditions of a pharmaceutical protein and collect X-ray data both in situ and ex situ.
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Submitted on : Tuesday, October 3, 2017 - 2:58:01 PM
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Charline Gerard, Gilles Ferry, Laurent Vuillard, Jean A Boutin, Léonard Chavas, et al.. Crystallization via tubing microfluidics permits both in situ and ex situ X-ray diffraction. Acta crystallographica. Section F, Structural biology communications, John Wiley & Sons Ltd,, 2017, 73 (10), pp.574 - 578. ⟨10.1107/S2053230X17013826⟩. ⟨hal-01493598v2⟩

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