Inferring Parameters in Genetic Regulatory Networks

Camilo La Rota (1) , Fabien Tarissan (2) , Leo Liberti (2)

1 IXXI - Institut Rhône-Alpin des systèmes complexes
2 LIX - Laboratoire d'informatique de l'École polytechnique [Palaiseau]

We formulate and solve the problem of determining the arc weights in a Genetic Regulatory Network (GRN) so that it presents observed states at given development stages.

Domaines: Informatique [cs]; Bio-informatique [q-bio.QM]; Réseaux et télécommunications [cs.NI]; Recherche opérationnelle [math.OC]

Camilo La Rota, Fabien Tarissan, Leo Liberti. Inferring Parameters in Genetic Regulatory Networks. Latin American Conference on Operational Research (CLAIO'08), 2008, Carthagène des Indes, Colombia. ⟨hal-01217839⟩