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[HIV infection and diabetes: experience and quality of life in patients with two chronic diseases].

Caroline Henry 1 Patricia Pavese 1 Myriam Blanc 1 José Labarère 2 Pascale Leclercq 3 Jean-Paul Brion 1
TIMC-IMAG - Techniques de l'Ingénierie Médicale et de la Complexité - Informatique, Mathématiques et Applications, Grenoble - UMR 5525, CHU Grenoble
Abstract : OBJECTIVES: Diabetes mellitus is frequently associated with HIV infection but there's only limited evidence regarding the control and impact of this co-morbidity. This study aimed to estimate the prevalence of diabetes, compliance with treatment, perception and quality of life of HIV patients with diabetes. METHODS: We conducted a cross-sectional study among patients treated for diabetes and registered in the DMI2 databasis in a French university hospital in January 2010. Clinical assessment and follow-up data were collected using chart review and self-administered questionnaires. Quality of life (MOS SF-12) and compliance with treatment (simplified medication adherence questionnaire) were assessed using validated scales. RESULTS: The prevalence of treated diabetes mellitus was 3.9% (29/748, 95% confidence interval, 2.6% to 5.5%). Among these 29 HIV diabetic patients, 93% had a virologic control of HIV infection while only 22% had well-controlled diabetes. Ninety-six percent of patients were scared to die from HIV-which was rated as the main pathology-compared with 71% of patients for diabetes. The mean score for physical quality of life was 43.1 (13.2), which was lower than estimates for overall population. Non-compliance with treatment was reported for 35% of patients. DISCUSSION: Although anti-retroviral treatments turned HIV infection into a chronic disease, patient perception was not altered. This study shows a better control of HIV infection than diabetes. We have to find out ways (e.g. patient education programs, annual multidisciplinary consultation...) to give the patient a global feel for his health thereby improving prognosis and quality of life.
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Submitted on : Thursday, July 11, 2013 - 12:51:32 PM
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Caroline Henry, Patricia Pavese, Myriam Blanc, José Labarère, Pascale Leclercq, et al.. [HIV infection and diabetes: experience and quality of life in patients with two chronic diseases].. La Presse medicale, Paris, Masson et Cie, 2011, 40 (10), pp.e463-70. ⟨10.1016/j.lpm.2011.05.019⟩. ⟨hal-00843432⟩



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