Innate immune defenses mediated by two ILC subsets are critical for protection against acute clostridium difficile infection, Cell Host Microbe, vol.18, pp.27-37, 2015. ,
Type 3 innate lymphoid cells maintain intestinal epithelial stem cells after tissue damage, J. Exp. Med, vol.212, pp.1783-1791, 2015. ,
The biology of innate lymphoid cells, Nature, vol.517, pp.293-301, 2015. ,
IL-1b, IL-4 and IL-12 control the fate of group 2 innate lymphoid cells in human airway inflammation in the lungs, Nat. Immunol, vol.17, pp.636-645, 2016. ,
T-bet and Eomes instruct the development of two distinct natural killer cell lineages in the liver and in the bone marrow, J. Exp. Med, vol.211, pp.563-577, 2014. ,
URL : https://hal.archives-ouvertes.fr/hal-00972070
Development, differentiation, and diversity of innate lymphoid cells, Immunity, vol.41, pp.354-365, 2014. ,
Interleukin-22 drives endogenous thymic regeneration in mice, Science, vol.336, pp.91-95, 2012. ,
Type I interferon restricts type 2 immunopathology through the regulation of group 2 innate lymphoid cells, Nat. Immunol, vol.17, pp.65-75, 2016. ,
Innate lymphoid cells: major players in inflammatory diseases, Nat. Rev. Immunol, vol.17, pp.665-678, 2017. ,
URL : https://hal.archives-ouvertes.fr/hal-01764670
Innate lymphoid cells. Innate lymphoid cells: a new paradigm in immunology, Science, vol.348, p.6566, 2015. ,
URL : https://hal.archives-ouvertes.fr/pasteur-01402714
NKp80 defines a critical step during human natural killer cell development, Cell Rep, vol.16, pp.379-391, 2016. ,
Intraepithelial type 1 innate lymphoid cells are a unique subset of IL-12-and IL-15-responsive IFN-g-producing cells, Immunity, vol.38, pp.769-781, 2013. ,
Critical role of p38 and GATA3 in natural helper cell function, J. Immunol, vol.191, pp.1818-1826, 2013. ,
Tumor immunoevasion by the conversion of effector NK cells into type 1 innate lymphoid cells, Nat. Immunol, vol.18, pp.1004-1015, 2017. ,
URL : https://hal.archives-ouvertes.fr/hal-01765092
Tissue residency of innate lymphoid cells in lymphoid and nonlymphoid organs, Science, vol.350, pp.981-985, 2015. ,
Intestinal epithelial tuft cells initiate type 2 mucosal immunity to helminth parasites, Nature, vol.529, pp.226-230, 2016. ,
URL : https://hal.archives-ouvertes.fr/hal-02187329
The spectrum and regulatory landscape of intestinal innate lymphoid cells are shaped by the microbiome, Cell, vol.166, pp.1231-1246, 2016. ,
Innate lymphoid cells regulate CD4+ T-cell responses to intestinal commensal bacteria, Nature, vol.498, pp.113-117, 2013. ,
Type 2 innate signals stimulate fibro/adipogenic progenitors to facilitate muscle regeneration, Cell, vol.153, pp.376-388, 2013. ,
A catch-22: Interleukin-22 and cancer, Eur J Immunol, vol.48, pp.15-31, 2018. ,
Interferon-l and interleukin 22 act synergistically for the induction of interferon-stimulated genes and control of rotavirus infection, Nat. Immunol, vol.16, pp.698-707, 2015. ,
Tuft cells, taste-chemosensory cells, orchestrate parasite type 2 immunity in the gut, Science, vol.351, pp.1329-1333, 2016. ,
The transcription factor GATA-3 controls cell fate and maintenance of type 2 innate lymphoid cells, Immunity, vol.37, pp.634-648, 2012. ,
IL-25-responsive, lineage-negative KLRG1(hi) cells are multipotential 'inflammatory' type 2 innate lymphoid cells, Nat. Immunol, vol.16, pp.161-169, 2015. ,
IL-22BP is regulated by the inflammasome and modulates tumorigenesis in the intestine, Nature, vol.491, pp.259-263, 2012. ,
Glial-cell-derived neuroregulators control type 3 innate lymphoid cells and gut defence, Nature, vol.535, pp.440-443, 2016. ,
Mechanisms to suppress ilc2-induced airway inflammation, p.95, 2016. ,
Retinoic acid differentially regulates the migration of innate lymphoid cell subsets to the gut, Immunity, vol.43, pp.107-119, 2015. ,
Innate lymphoid cells sustain colon cancer through production of interleukin-22 in a mouse model, J. Exp. Med, vol.210, pp.917-931, 2013. ,
Natural aryl hydrocarbon receptor ligands control organogenesis of intestinal lymphoid follicles, Science, vol.334, pp.1561-1565, 2011. ,
Essential, dose-dependent role for the transcription factor Gata3 in the development of IL-5 + and IL-13 + type 2 innate lymphoid cells, Proc. Natl. Acad. Sci. USA, vol.110, pp.10240-10245, 2013. ,
URL : https://hal.archives-ouvertes.fr/pasteur-00842573
A T-bet gradient controls the fate and function of CCR6-RORgt+ innate lymphoid cells, Nature, vol.494, pp.261-265, 2013. ,
Differentiation of type 1 ILCs from a common progenitor to all helper-like innate lymphoid cell lineages, Cell, vol.157, pp.340-356, 2014. ,
The neuropeptide neuromedin U stimulates innate lymphoid cells and type 2 inflammation, Nature, vol.549, pp.282-286, 2017. ,
Distinct gene regulatory pathways for human innate versus adaptive lymphoid cells, Cell, vol.165, pp.1134-1146, 2016. ,
AHR drives the development of gut ILC22 cells and postnatal lymphoid tissues via pathways dependent on and independent of Notch, Nat. Immunol, vol.13, pp.144-151, 2011. ,
Activated type 2 innate lymphoid cells regulate beige fat biogenesis, Cell, vol.160, pp.74-87, 2015. ,
Adipose natural killer cells regulate adipose tissue macrophages to promote insulin resistance in obesity, Cell Metab, vol.23, pp.685-698, 2016. ,
IL-12 drives functional plasticity of human group 2 innate lymphoid cells, J. Exp. Med, vol.213, pp.569-583, 2016. ,
Systemic human ILC precursors provide a substrate for tissue ILC differentiation, Cell, vol.168, pp.1086-1100, 2017. ,
Interleukin-22 promotes intestinal-stem-cell-mediated epithelial regeneration, Nature, vol.528, pp.560-564, 2015. ,
Influence of the transcription factor RORgammat on the development of NKp46+ cell populations in gut and skin, Nat. Immunol, vol.10, pp.75-82, 2009. ,
URL : https://hal.archives-ouvertes.fr/hal-00403251
Developing lymph nodes collect CD4+CD3-LTbeta+ cells that can differentiate to APC, NK cells, and follicular cells but not T or B cells, Immunity, vol.7, pp.493-504, 1997. ,
Retinoic acid expression associates with enhanced IL-22 production by gd T cells and innate lymphoid cells and attenuation of intestinal inflammation, J. Exp. Med, vol.210, pp.1117-1124, 2013. ,
Human IL-25-and IL-33-responsive type 2 innate lymphoid cells are defined by expression of CRTH2 and CD161, Nat. Immunol, vol.12, pp.1055-1062, 2011. ,
The transcription factor GATA3 is essential for the function of human type 2 innate lymphoid cells, Immunity, vol.37, pp.649-659, 2012. ,
Innate lymphoid type 2 cells sustain visceral adipose tissue eosinophils and alternatively activated macrophages, J. Exp. Med, vol.210, pp.535-549, 2013. ,
Interleukin-33 and interferon-g counter-regulate group 2 innate lymphoid cell activation during immune perturbation, Immunity, vol.43, pp.161-174, 2015. ,
Innate lymphoid cells promote lung-tissue homeostasis after infection with influenza virus, Nat Immunol, vol.12, pp.1045-1054, 2011. ,
IL-33 promotes an innate immune pathway of intestinal tissue protection dependent on amphiregulin-EGFR interactions, Proc Natl Acad Sci, vol.112, pp.10762-10767, 2015. ,
b 2 -adrenergic receptor-mediated negative regulation of group 2 innate lymphoid cell responses, Science, vol.359, pp.1056-1061, 2018. ,
Innate production of T( H) 2 cytokines by adipose tissue-associated c-Kit( +) Sca-1( + ) lymphoid cells, Nature, vol.463, pp.540-544, 2010. ,
Interferon and IL-27 antagonize the function of group 2 innate lymphoid cell function and type 2 innate immune responses, Nat. Immunol, vol.17, pp.76-86, 2016. ,
Microbiota-dependent crosstalk between macrophages and ILC3 promotes intestinal homeostasis, Science, vol.343, p.1249288, 2014. ,
Tissue-resident memory T cells: local specialists in immune defence, Nat. Rev. Immunol, vol.16, pp.79-89, 2016. ,
Nuocytes represent a new innate effector leukocyte that mediates type-2 immunity, Nature, vol.464, pp.1367-1370, 2010. ,
Type 2 innate lymphoid cells control eosinophil homeostasis, Nature, vol.502, pp.245-248, 2013. ,
Adipose-resident group 1 innate lymphoid cells promote obesity-associated insulin resistance, Immunity, vol.45, pp.428-441, 2016. ,
IL-1 is a critical regulator of group 2 innate lymphoid cell function and plasticity, Nat. Immunol, vol.17, pp.646-655, 2016. ,
, , 2014.
, MHCII-mediated dialog between group 2 innate lymphoid cells and CD4(+) T cells potentiates type 2 immunity and promotes parasitic helminth expulsion, Immunity, vol.41, pp.283-295
Allergic host defences, Nature, vol.484, pp.465-472, 2012. ,
Differential RET signaling pathways drive development of the enteric lymphoid and nervous systems, Sci. Signal, vol.5, p.55, 2012. ,
, , 2016.
, ILC3 GM-CSF production and mobilisation orchestrate acute intestinal inflammation. eLife 5, e10066
Liver-resident NK cells confer adaptive immunity in skin-contact inflammation, J. Clin. Invest, vol.123, pp.1444-1456, 2013. ,
Systemically dispersed innate IL-13-expressing cells in type 2 immunity, Proc. Natl. Acad. Sci. USA, vol.107, pp.11489-11494, 2010. ,
Host resistance to endotoxic shock requires the neuroendocrine regulation of group 1 innate lymphoid cells, J. Exp. Med, vol.214, pp.3531-3541, 2017. ,
URL : https://hal.archives-ouvertes.fr/hal-01764683
The transcription factor T-bet is essential for the development of NKp46+ innate lymphocytes via the Notch pathway, Nat. Immunol, vol.14, pp.389-395, 2013. ,
Complementarity and redundancy of IL-22-producing innate lymphoid cells, Nat. Immunol, vol.17, pp.179-186, 2016. ,
URL : https://hal.archives-ouvertes.fr/hal-01440245
Identification of a human natural killer cell lineagerestricted progenitor in fetal and adult tissues, Immunity, vol.43, pp.394-407, 2015. ,
Transcriptional programs define molecular characteristics of innate lymphoid cell classes and subsets, Nat. Immunol, vol.16, pp.306-317, 2015. ,
RORgammat and commensal microflora are required for the differentiation of mucosal interleukin 22-producing NKp46+ cells, Nat. Immunol, vol.10, pp.83-91, 2009. ,
Microbial flora drives interleukin 22 production in intestinal NKp46 + cells that provide innate mucosal immune defense, Immunity, vol.29, pp.958-970, 2008. ,
URL : https://hal.archives-ouvertes.fr/pasteur-01402754
Distinct requirements for T-bet in gut innate lymphoid cells, J. Exp. Med, vol.209, pp.2331-2338, 2012. ,
A progenitor cell expressing transcription factor RORgt generates all human innate lymphoid cell subsets, Immunity, vol.44, pp.1140-1150, 2016. ,
Alternative activation generates IL-10 producing type 2 innate lymphoid cells, Nat. Commun, vol.8, 1900. ,
Developmental acquisition of regulomes underlies innate lymphoid cell functionality, Cell, vol.165, pp.1120-1133, 2016. ,
, , 2017.
, Neuropilin-1 is expressed on lymphoid tissue residing lti-like group 3 innate lymphoid cells and associated with ectopic lymphoid aggregates, Cell Rep, vol.18, pp.1761-1773
Inflammatory triggers associated with exacerbations of COPD orchestrate plasticity of group 2 innate lymphoid cells in the lungs, Nat Immunol, vol.17, pp.626-635, 2016. ,
,
, CD4(+) lymphoid tissue-inducer cells promote innate immunity in the gut, Immunity, vol.34, pp.122-134
, , 2012.
, Innate lymphoid cells promote anatomical containment of lymphoid-resident commensal bacteria, Science, vol.336, pp.1321-1325
Adaptation of innate lymphoid cells to a micronutrient deficiency promotes type 2 barrier immunity, Science, vol.343, pp.432-437, 2014. ,
Innate lymphoid cells-a proposal for uniform nomenclature, Nat. Rev. Immunol, vol.13, pp.145-149, 2013. ,
Pulmonary neuroendocrine cells amplify allergic asthma responses, Science, vol.360, 2018. ,
Maternal retinoids control type 3 innate lymphoid cells and set the offspring immunity, Nature, vol.508, pp.123-127, 2014. ,
Neuronal-immune system cross-talk in homeostasis, Science, vol.359, pp.1465-1466, 2018. ,
Tyrosine kinase receptor RET is a key regulator of Peyer's patch organogenesis, Nature, vol.446, pp.547-551, 2007. ,
Evidence of innate lymphoid cell redundancy in humans, Nat. Immunol, vol.17, pp.1291-1299, 2016. ,
Transforming growth factor-b and Notch ligands act as opposing environmental cues in regulating the plasticity of type 3 innate lymphoid cells, Sci. Signal, vol.9, p.46, 2016. ,
Innate or adaptive immunity? The example of natural killer cells, Science, vol.331, pp.44-49, 2011. ,
URL : https://hal.archives-ouvertes.fr/hal-00611585
Tuft-cell-derived IL-25 regulates an intestinal ILC2-epithelial response circuit, Nature, vol.529, pp.221-225, 2016. ,
Regulated expression of nuclear receptor RORgt confers distinct functional fates to NK cell receptor-expressing RORgt(+) innate lymphocytes, Immunity, vol.33, pp.736-751, 2010. ,
A thymic pathway of mouse natural killer cell development characterized by expression of GATA-3 and CD127, Nat. Immunol, vol.7, pp.1217-1224, 2006. ,
URL : https://hal.archives-ouvertes.fr/pasteur-00362040
The neuropeptide NMU amplifies ILC2-driven allergic lung inflammation, Nature, vol.549, pp.351-356, 2017. ,
Regulatory innate lymphoid cells control innate intestinal inflammation, Cell, vol.171, pp.201-216, 2017. ,
ILC1 confer early host protection at initial sites of viral infection, Cell, vol.171, pp.795-808, 2017. ,
NK cells link obesity-induced adipose stress to inflammation and insulin resistance, Nat. Immunol, vol.16, pp.376-385, 2015. ,
, , 2016.
, Critical role of fatty acid metabolism in ILC2-mediated barrier protection during malnutrition and helminth infection, J. Exp. Med, vol.213, pp.1409-1418
Transcription factor RORa is critical for nuocyte development, Nat. Immunol, vol.13, pp.229-236, 2012. ,
Emerging functions of amphiregulin in orchestrating immunity, inflammation, and tissue repair, Immunity, vol.42, pp.216-226, 2015. ,
Interleukin-22 but not interleukin-17 provides protection to hepatocytes during acute liver inflammation, Immunity, vol.27, pp.647-659, 2007. ,
Cutting edge: notch signaling promotes the plasticity of group-2 innate lymphoid cells, J. Immunol, vol.198, pp.1798-1803, 2017. ,