Recurrent CA1 collateral axons in developing rat hippocampus.

Laurent Aniksztejn (1) , Michaël Demarque (1) , Youri Morozov (1) , Yehezkel Ben-Ari (1) , Alfonso Represa (1)

1 Epilepsie et ischémie cérébrale

Rat perinatal (E20-P0) CA1 pyramidal neurons were either synaptically active or silent. We show here that, during this developmental period, active but not silent cells form recurrent axon-collaterals that invade the radiatum and the lacunosum moleculare strata. These recurrents were never observed in adult rats. We propose that these transient recurrent axons may participate in the activity-dependent modulation of the synaptogenesis

Domains: Cellular Biology

Laurent Aniksztejn, Michaël Demarque, Youri Morozov, Yehezkel Ben-Ari, Alfonso Represa. Recurrent CA1 collateral axons in developing rat hippocampus.. Brain Research, 2001, 913 (2), pp.195-200. ⟨inserm-00484929⟩