A Web of Circadian Pacemakers

Ueli Schibler (1) , Paolo Sassone-Corsi (2)

1 UNIGE - Université de Genève = University of Geneva
2 IGBMC - Institut de génétique et biologie moléculaire et cellulaire

The mammalian circadian timing system is composed of almost as many individual clocks as there are cells. These countless oscillators have to be synchronized by a central pacemaker to coordinate temporal physiology and behavior. Recently, there has been some progress in understanding the relationship and communication mechanisms between central and peripheral clocks.

Domaines: Biologie cellulaire

Ueli Schibler, Paolo Sassone-Corsi. A Web of Circadian Pacemakers. Cell, 2002, 111 (7), pp.919-922. ⟨10.1016/s0092-8674(02)01225-4⟩. ⟨hal-04142715⟩