MagPure chip: an immunomagnetic-based microfluidic device for high purification of circulating tumor cells from liquid biopsies

Lucie Descamps (1) , Jessica Garcia (2) , David Barthelemy (2) , Emmanuelle Laurenceau (1) , Léa Payen (2) , Damien Le Roy (3) , A.-L. Deman (1)

1 INL - DSE - INL - Dispositifs pour la Santé et l’Environnement
2 CICLY - Centre pour l'innovation en cancérologie de Lyon
3 iLM - ENERGIE - iLM - Transport, Nanomagnétisme et Matériaux pour l'Énergie

The isolation of circulating tumor cells (CTCs) directly from blood, as a liquid biopsy, could lead to a paradigm shift in cancer care. The MagPure chip provides a powerful tool for subsequent purification of CTCs and dissection of their clinical information.

Domaines: Sciences de l'ingénieur [physics]

Lucie Descamps, Jessica Garcia, David Barthelemy, Emmanuelle Laurenceau, Léa Payen, et al.. MagPure chip: an immunomagnetic-based microfluidic device for high purification of circulating tumor cells from liquid biopsies. Lab on a Chip, 2022, 22 (21), pp.4151-4166. ⟨10.1039/d2lc00443g⟩. ⟨hal-04137731⟩