Asymmetric expression of antivin/lefty1 in the early chick embryo

Yoshiyasu Ishimaru (1) , Hidefumi Yoshioka (1) , Hirotaka Tao (1) , Bernard Thisse (2) , Christine Thisse (2) , Christopher V.E. Wright (3) , Hiroshi Hamada (4, 5) , Hideyo Ohuchi (6) , Sumihare Noji (1)

1 Tokushima University
2 IGBMC - Institut de Génétique et de Biologie Moléculaire et Cellulaire
3 Vanderbilt University School of Medicine [Nashville]
4 Osaka University [Osaka]
5 CREST [Saitama, Japan]
6 Kyoto University

Mammalian lefty and zebrafish antivin, highly related to lefty, are shown to be expressed asymmetrically and involved in the specification of the left body side of early embryos. We isolated a chick homologue of the antivin/lefty1 cDNA and studied its expression pattern during early chick development. We found that antivin/lefty1 is expressed asymmetrically on the left side of the prospective floorplate, notochord and lateral plate mesoderm of the chick embryo.

Domaines: Sciences du Vivant [q-bio]

Yoshiyasu Ishimaru, Hidefumi Yoshioka, Hirotaka Tao, Bernard Thisse, Christine Thisse, et al.. Asymmetric expression of antivin/lefty1 in the early chick embryo. Mechanisms of Development, 2000, 90 (1), pp.115-118. ⟨10.1016/S0925-4773(99)00232-4⟩. ⟨hal-04093558⟩