Design and synthesis of active vitamin D analogs

Silvina Eduardo-Canosa , Ramón Fraga , Rita Sigüeiro , Maria Marco , Natacha Rochel (1, 2) , Dino Moras (1, 2) , Antonio Mouriño

1 IGBMC - Institut de génétique et biologie moléculaire et cellulaire
2 IGBMC - Institut de Génétique et de Biologie Moléculaire et Cellulaire

A review of the design and synthesis of structural analogs of the vitamin D hormone recently investigated in our laboratories, and the first report on a new class of vitamin D analogs characterized by an aromatic D-ring, is described.

Domaines: Biochimie, Biologie Moléculaire

Silvina Eduardo-Canosa, Ramón Fraga, Rita Sigüeiro, Maria Marco, Natacha Rochel, et al.. Design and synthesis of active vitamin D analogs. Journal of Steroid Biochemistry and Molecular Biology, 2010, 121 (1-2), pp.7-12. ⟨10.1016/j.jsbmb.2010.03.036⟩. ⟨hal-04031311⟩