A Modular Assembly of Chiral Oxazolinylcarbene–Rhodium Complexes: Efficient Phosphane-Free Catalysts for the Asymmetric Hydrosilylation of Dialkyl Ketones

Lutz Gade (1, 2) , Vincent César (1) , Stéphane Bellemin-Laponnaz (1)

1 CMTC - Chimie des métaux de transition et catalyse
2 Anorganisch-Chemisches Institut der Universität Heidelberg

A novel class of chiral bidentate ligands with a carbene and an oxazoline moiety is obtained by the coupling of N-arylimidazoles and a 2-bromooxazoline derivative. The rhodium complex 1 catalyzes the hydrosilylation of aryl alkyl ketones and otherwise problematic dialkyl ketones in high yields and good enantioselectivities (up to 95 % ee).

Mots clés: Asymmetric catalysis; Carbene ligands; Hydrosilylation; Ketones; Rhodium

Domaines: Chimie de coordination

Lutz Gade, Vincent César, Stéphane Bellemin-Laponnaz. A Modular Assembly of Chiral Oxazolinylcarbene–Rhodium Complexes: Efficient Phosphane-Free Catalysts for the Asymmetric Hydrosilylation of Dialkyl Ketones. Angewandte Chemie International Edition, 2004, 43 (8), pp.1014-1017. ⟨10.1002/anie.200353133⟩. ⟨hal-03710297⟩