The Nucleotide Sequence, DNA Damage Location, and Protein Stoichiometry Influence the Base Excision Repair Outcome at CAG/CTG Repeats
Agathi-Vasiliki Goula
(1)
,
Christopher Pearson
(2)
,
Julie Della Maria
(3)
,
Yvon Trottier
(1)
,
Alan Tomkinson
(3)
,
David Wilson
(4)
,
Karine Merienne
(1)
1
IGBMC -
Institut de Génétique et de Biologie Moléculaire et Cellulaire
2 Genetics and Genome Biology, The Hospital for Sick Children, TMDT Building, 101 College Street, 15th Floor, Room 15-312, East Tower, Toronto, ON, M5G 1L7 Canada, and Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada
3 Department of Radiation Oncology and Marlene and Stewart Greenebaum Cancer Center, University of Maryland School of Medicine, Baltimore, Maryland 21201, United States
4 Laboratory of Molecular Gerontology, National Institute on Aging, National Institutes of Health, Baltimore, Maryland 21224, United States
2 Genetics and Genome Biology, The Hospital for Sick Children, TMDT Building, 101 College Street, 15th Floor, Room 15-312, East Tower, Toronto, ON, M5G 1L7 Canada, and Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada
3 Department of Radiation Oncology and Marlene and Stewart Greenebaum Cancer Center, University of Maryland School of Medicine, Baltimore, Maryland 21201, United States
4 Laboratory of Molecular Gerontology, National Institute on Aging, National Institutes of Health, Baltimore, Maryland 21224, United States