Skip to Main content Skip to Navigation
Journal articles

Untargeted Metabolomics Reveals a Complex Impact on Different Metabolic Pathways in Scallop Mimachlamys varia (Linnaeus, 1758) after Short-Term Exposure to Copper at Environmental Dose

Abstract : Ports are a good example of how coastal environments, gathering a set of diverse ecosystems, are subjected to pollution factors coming from human activities both on land and at sea. Among them, trace element as copper represents a major factor. Abundant in port ecosystem, copper is transported by runoff water and results from diverse port features (corrosion of structures, fuel, anti-fouling products, etc.). The variegated scallop Mimachlamys varia is common in the Atlantic port areas and is likely to be directly influenced by copper pollution, due to its sessile and filtering lifestyle. Thus, the aim of the present study is to investigate the disruption of the variegated scallop metabolism, under a short exposure (48 h) to a copper concentration frequently encountered in the waters of the largest marina in Europe (82 μg/L). For this, we chose a non-targeted metabolomic approach using ultra-high performance liquid chromatography coupled to high resolution mass spectrometry (UHPLC-HRMS), offering a high level of sensitivity and allowing the study without a priori of the entire metabolome. We described 28 metabolites clearly modulated by copper. They reflected the action of copper on several biological functions such as osmoregulation, oxidative stress, reproduction and energy metabolism.
Document type :
Journal articles
Complete list of metadata

https://hal.archives-ouvertes.fr/hal-03476592
Contributor : Marianne Graber Connect in order to contact the contributor
Submitted on : Monday, December 13, 2021 - 9:18:05 AM
Last modification on : Wednesday, May 18, 2022 - 11:20:05 AM

Links full text

Identifiers

Collections

Citation

Vincent Hamani, Pascaline Ory, Pierre-Edouard Bodet, Laurence Murillo, Marianne Graber. Untargeted Metabolomics Reveals a Complex Impact on Different Metabolic Pathways in Scallop Mimachlamys varia (Linnaeus, 1758) after Short-Term Exposure to Copper at Environmental Dose. Metabolites, MDPI, 2021, 11 (12), pp.862. ⟨10.3390/metabo11120862⟩. ⟨hal-03476592⟩

Share

Metrics

Record views

14