Bicyclic 5-6 Systems with One Bridgehead (Ring Junction) Nitrogen Atom: Four Extra Heteroatoms 2:2

Aurélie Claraz (1)

1 ICSN - Institut de Chimie des Substances Naturelles

Bicyclic 5-6 systems with one ring junction nitrogen atom and two extra heteroatoms (nitrogen, sulfur and oxygen) in both cycles are reviewed in this chapter. Literature data from 2007 to 2019 are considered. Among all the possible ring systems, 18 different structural backbones have been found in this period covering various triazolothiadiazines, oxadiazolotriazines, thiadiazolotriazines, and triazolotriazines derivatives. Fully as long as partially unsaturated regioisomers are examined. Most references deal with [1,2,4]triazolo[3,4-b][1,3,4]thiadiazines. Theoretical methods, structural determinations and thermodynamic properties of the aforementioned ring systems are briefly discussed while their reactivity and syntheses are detailed. Notable applications of important compounds are also listed.

Domaines: Chimie organique

Aurélie Claraz. Bicyclic 5-6 Systems with One Bridgehead (Ring Junction) Nitrogen Atom: Four Extra Heteroatoms 2:2. Comprehensive Heterocyclic Chemistry IV, 11, Elsevier, pp.802-858, 2022, ⟨10.1016/B978-0-12-818655-8.00086-X⟩. ⟨hal-03452150⟩