Hydroarylation of N ‐Allenyl Derivatives Catalyzed by Copper

Racha Abed Ali Abdine (1) , Lucas Pagès (1) , Marc Taillefer (1) , Florian Monnier (1)

1 ICGM - Institut Charles Gerhardt Montpellier - Institut de Chimie Moléculaire et des Matériaux de Montpellier

An additive-free copper catalytic system was used to perform the addition of (hetero)aryl nucleophiles to N-allenyl derivatives. This intermolecular C–C bond formation occurs with both complete regio- and stereoselectivity to afford the linear (E) allylic product with moderate to excellent yields. This atom economical method is the first example of hydroarylation of allenes catalyzed by copper.

Mots clés: allenes; copper; hydroarylation; allylic compounds; arenes; homogeneous catalysis

Domaines: Chimie organique; Catalyse

Racha Abed Ali Abdine, Lucas Pagès, Marc Taillefer, Florian Monnier. Hydroarylation of N ‐Allenyl Derivatives Catalyzed by Copper. European Journal of Organic Chemistry, 2020, 2020 (48), pp.7466-7469. ⟨10.1002/ejoc.202001333⟩. ⟨hal-03450694⟩