Protective role of the mitochondrial fusion protein OPA1 in hypertension

Pauline Robert (1) , Phuc Minh Chau Nguyen , Alexis Richard , Céline Grenier , Arnaud Chevrollier , Mathilde Munier , Linda Grimaud , Coralyne Proux , Tristan Champin , Eric Lelièvre , Emmanuelle Sarzi , Emilie Vessières , Samir Henni , Delphine Prunier , Pascal Reynier , Guys Lenaers , Céline Fassot (1) , Daniel Henrion (1) , Laurent Loufrani (1)

1 MITOVASC - MitoVasc - Physiopathologie Cardiovasculaire et Mitochondriale

Mots clés: AngII; angiotensin II; DHE; dihydroethidium; DMEM; Dulbecco's Modified Eagle Medium; DOCA; deoxycorticosterone acetate; Drp1; dynamin-related protein; Fis1; mitochondrial fission 1 protein; L-NAME; L-N G -nitroarginine methyl ester; MA; mesenteric arteries; Mfn1; mitofusin 1; Mfn2; mitofusin 2; Opa1; optic atrophy 1; PSS; physiological salt solution; ROS; reactive oxygen species; SHR; spontaneously hypertensive rat

Domaines: Physiologie [q-bio.TO]

Pauline Robert, Phuc Minh Chau Nguyen, Alexis Richard, Céline Grenier, Arnaud Chevrollier, et al.. Protective role of the mitochondrial fusion protein OPA1 in hypertension. FASEB Journal, 2021, 35, ⟨10.1096/fj.202000238rrr⟩. ⟨hal-03379614⟩