Mn-based 2D layered nanomaterials for boosting the MRI signal

Brindusa Dragoi , Cristina Mariana Uritu , Laurentiu Agrigoroaie , Doina Lutic , Thomas Cacciaguerra , Vasile Hulea (1) , Eugen Carasevici

1 ICGM - Institut Charles Gerhardt Montpellier - Institut de Chimie Moléculaire et des Matériaux de Montpellier

Manganese-based 2D nanoparticles with increased longitudinal relaxivity (r1) in MRI were synthesised by co-precipitation at low suprasaturation. The results of physico-chemical characterizations, i.e., XRD, FT-IR, DR UV–vis, N2 physisorption, and SEM, showed an excellent 2D nanomaterial in which manganese is predominantly incorporated as Mn2+ and Mn3+. The r1 relaxivity obtained on a 1.0 Tesla apparatus at pH = 7.4 is significantly improved (r1 = 1.298 mM1 s1) as compared with other similar layered materials containing manganese.

Mots clés: Manganese; LDH; Contrast; agent MRI

Domaines: Chimie

Brindusa Dragoi, Cristina Mariana Uritu, Laurentiu Agrigoroaie, Doina Lutic, Thomas Cacciaguerra, et al.. Mn-based 2D layered nanomaterials for boosting the MRI signal. Materials Letters, 2021, 288, pp.129331. ⟨10.1016/j.matlet.2021.129331⟩. ⟨hal-03131801⟩