Identification of a Paracrine Signaling Mechanism Linking CD34high Progenitors to the Regulation of Visceral Fat Expansion and Remodeling

Karla Maria Pires , Márcio Buffolo , Karla Maria Pires , Maroua Ferhat , Olesya Ilkun , Aman Makaju , Alan Achenbach , Faith Bowman , Donald L Atkinson , William L Holland , Ez-Zoubir Amri (1) , Bhagirath Chaurasia , Sarah Franklin , Sihem Boudina

1 IBV - Institut de Biologie Valrose

Highlights d Visceral fat contains subsets of stromal cells with distinct adipogenic potential d Cd34 high stromal cells inhibit adipogenesis through the secretion of soluble factors d Cd34 high stromal cells cause tissue remodeling and metabolic dysfunction in vivo

Domaines: Sciences du Vivant [q-bio]

Karla Maria Pires, Márcio Buffolo, Karla Maria Pires, Maroua Ferhat, Olesya Ilkun, et al.. Identification of a Paracrine Signaling Mechanism Linking CD34high Progenitors to the Regulation of Visceral Fat Expansion and Remodeling. Cell Reports, 2019, 29 (2), pp.270-282.e5. ⟨10.1016/j.celrep.2019.08.092⟩. ⟨hal-03059061⟩