Design, synthesis and biological evaluation of antimicrobial diarylimine and –amine compounds targeting the interaction between the bacterial NusB and NusE proteins

Yangyi Qiu , Shu Ting Chan , Lin Lin , Tsun Lam Shek , Tsz Fung Tsang , Nilakshi Barua , Yufeng Zhang , Margaret Ip , Paul Kay-Sheung Chan , Nicolas Blanchard (1) , Gilles Hanquet (1) , Zhong Zuo , Xiao Yang , Cong Ma

1 LIMA - Laboratoire d'innovation moléculaire et applications

Domaines: Chimie; Sciences du Vivant [q-bio]

Yangyi Qiu, Shu Ting Chan, Lin Lin, Tsun Lam Shek, Tsz Fung Tsang, et al.. Design, synthesis and biological evaluation of antimicrobial diarylimine and –amine compounds targeting the interaction between the bacterial NusB and NusE proteins. European Journal of Medicinal Chemistry, 2019, 178, pp.214-231. ⟨10.1016/j.ejmech.2019.05.090⟩. ⟨hal-03054499⟩