Skip to Main content Skip to Navigation
Book sections

Thermodynamic Approaches in Flux Analysis

Abstract : Networks of reactions inside the cell are constrained by the laws of mass and energy balance. Constrained-based modelling (CBM) is the most used method to describe the mass balance of metabolic network. The main key concepts in CBM are stoichiometric analysis such as elementary flux mode analysis or flux balance analysis. Some of these methods have focused on adding thermodynamics constraints to eliminate non-physical fluxes or inconsistencies in the metabolic system. Here, we review the main different approaches and how they tackle the different class of problems.
Document type :
Book sections
Complete list of metadata
Contributor : Sabine Peres <>
Submitted on : Thursday, October 15, 2020 - 2:32:16 PM
Last modification on : Monday, July 19, 2021 - 10:57:58 AM



Sabine Peres, Vincent Fromion. Thermodynamic Approaches in Flux Analysis. Metabolic Flux Analysis in Eukaryotic Cells, pp.359-367, 2020, ⟨10.1007/978-1-0716-0159-4_17⟩. ⟨hal-02968157⟩



Record views