CORS (CROM20): A new high-prevalence antigen in the Cromer blood group system.

Cédric Vrignaud (1) , Jacques Chiaroni (2, 3) , Elisabeth Durieux-Roussel (3) , Caroline Le van Kim (1) , Slim Azouzi (1) , Thierry Peyrard (1)

1 Labex Gr-Ex - Laboratoire d'Excellence : Biogenèse et pathologies du globule rouge
2 ADES - Anthropologie bio-culturelle, Droit, Ethique et Santé
3 EFS - Etablissement Français du Sang Provence-Alpes Côte-d'Azur et Corse

The Cromer blood group system consists of 19 antigens (16 of high prevalence and 3 of low prevalence). This study describes the identification and characterization of a new Cromer high-prevalence antigen, named CORS. The CORS-negative proband carries a c.713G>A substitution in the CD55 gene, resulting in the substitution of glycine 238 into a glutamic acid (p.Gly238Glu).

Domaines: Sciences du Vivant [q-bio]

Cédric Vrignaud, Jacques Chiaroni, Elisabeth Durieux-Roussel, Caroline Le van Kim, Slim Azouzi, et al.. CORS (CROM20): A new high-prevalence antigen in the Cromer blood group system.. Transfusion, 2020, ⟨10.1111/trf.16052⟩. ⟨hal-02939073⟩