The intellectual disability of trisomy 21: differences in gene expression in a case series of patients with lower and higher IQ

Andre Megarbane (1) , Florian Noguier (2) , Samantha Stora (3) , Laurent Manchon (4) , Clotilde Mircher (3) , Roman Bruno , Nathalie Dorison (5) , Fabien Pierrat (6) , Marie-Odile Réthoré (7) , Bernadette Trentin (8) , Aimé Ravel (3) , Marine Morent , Gerard Lefranc (9) , David Piquemal (8)

1 IBCP - Institut de biologie et chimie des protéines [Lyon]
2 ACOBIOM
3 Institut Jérôme Lejeune
4 IGMM - Institut de Génétique Moléculaire de Montpellier
5 Fondation Ophtalmologique Adolphe de Rothschild [Paris]
6 Skuld-Tech - Skuld-Tech, biotechnology company
7 Laboratoire d'Anatomie pathologique
8 Skuldtech. Cap Delta - ZAC Euromedecine II. 1682
9 UM2 - Université Montpellier 2 - Sciences et Techniques

Domaines: Sciences du Vivant [q-bio]; Biologie cellulaire

Andre Megarbane, Florian Noguier, Samantha Stora, Laurent Manchon, Clotilde Mircher, et al.. The intellectual disability of trisomy 21: differences in gene expression in a case series of patients with lower and higher IQ. European Journal of Human Genetics, 2013, 21 (11), pp.1253-1259. ⟨10.1038/ejhg.2013.24⟩. ⟨hal-02867259⟩