Intraoperative ventilator settings and their association with postoperative pulmonary complications in neurosurgical patients: post-hoc analysis of LAS VEGAS study

Chiara Robba (1, 2) , Sabrine Hemmes (3) , Ary Serpa Neto (3) , Thomas Bluth (4) , Jaume Canet , Michael Hiesmayr (5) , M Wiersma Hollmann , Gary Mills , Marcos Vidal Melo (6) , Christian Putensen , Samir Jaber (7, 8) , Werner Schmid (9) , Paolo Severgnini (10) , Hermann Wrigge , Denise Battaglini , Lorenzo Ball , Marcelo Gama de Abreu , Marcus Schultz (11) , Paolo Pelosi (12)

1 Policlinico San Martino,
2 Anaesthesia and Intensive Care, San Martino Policlinico Hospital, IRCCS for Oncology and Neurosciences, Largo Rosanna Benzi 8, 16131, Genoa, Italy
3 UvA - University of Amsterdam [Amsterdam] = Universiteit van Amsterdam
4 Department of Anaesthesiology and Intensive Care Medicine, Pulmonary engineering group, University Hospital Carl Gustav Carus, Technische Universitat Dresden, Dresden, Germany
5 Division of Cardiac, Thoracic, Vascular Anaesthesia and Intensive Care
6 Massachusetts General Hospital, Harvard Medical School, Boston, USA. 17
7 PhyMedExp - Physiologie & médecine expérimentale du Cœur et des Muscles [U 1046]
8 CHRU Montpellier - Centre Hospitalier Régional Universitaire [Montpellier]
9 Medizinische Universität Wien = Medical University of Vienna
10 Uninsubria - Universitá degli Studi dell’Insubria = University of Insubria [Varese]
11 Department of Intensive Care, Academic Medical Center,
12 IRCCS San Martino IST

Limited information is available regarding intraoperative ventilator settings and the incidence of postoperative pulmonary complications (PPCs) in patients undergoing neurosurgical procedures. The aim of this post-hoc analysis of the 'Multicentre Local ASsessment of VEntilatory management during General Anaesthesia for Surgery' (LAS VEGAS) study was to examine the ventilator settings of patients undergoing neurosurgical procedures, and to explore the association between perioperative variables and the development of PPCs in neurosurgical patients.

Mots clés: LAS VEGAS; Mechanical ventilation; Neurosurgery; Postoperative pulmonary complications

Domaines: Sciences du Vivant [q-bio]

Chiara Robba, Sabrine Hemmes, Ary Serpa Neto, Thomas Bluth, Jaume Canet, et al.. Intraoperative ventilator settings and their association with postoperative pulmonary complications in neurosurgical patients: post-hoc analysis of LAS VEGAS study. BMC Anesthesiology, 2020, 20 (1), pp.73. ⟨10.1186/s12871-020-00988-x⟩. ⟨hal-02532009⟩