BIOMIMETIC SPIKE-TIMING BASED IONIC MICROSTIMULATION FOR NEURON CULTURE

Stephany Mai Nishikawa , Farad Khoyratee (1) , Soo Hyeon Kim , Yoshiho Ikeuchi (2) , Kazuyuki Aihara (2) , Teruo Fujii (3) , Timothée Levi (1)

1 IMS - Laboratoire de l'intégration, du matériau au système
2 IIS - Institute of Industrial Science
3 LIMMS - Laboratory for Integrated Micro Mechatronics Systems

Neurodegenerative diseases are incurable and debilitating conditions that influence cognitive and/or motor functions in millions of people worldwide. Neuroprosthesis are used today to support the quality of life but have yet to improve in their power consumption and biocompatibility issues. For the future realization of neuroprosthesis, understanding the neurophysiological behaviors and the investigations on the interaction of neuronal cell assemblies is therefore essential. Here, we propose a novel microfluidic system to investigate the response of the neurons directly stimulated by the potassium ions in vitro in biomimetic timing.

Mots clés: Microfluidics; Spiking Neural Network; Neurons; Ionic micro-stimulation

Domaines: Sciences de l'ingénieur [physics]

Stephany Mai Nishikawa, Farad Khoyratee, Soo Hyeon Kim, Yoshiho Ikeuchi, Kazuyuki Aihara, et al.. BIOMIMETIC SPIKE-TIMING BASED IONIC MICROSTIMULATION FOR NEURON CULTURE. ICAROB, Jan 2019, Beppu, Japan. ⟨hal-02484012⟩