HAL will be down for maintenance from Friday, June 10 at 4pm through Monday, June 13 at 9am. More information
Skip to Main content Skip to Navigation
Journal articles

Prevalence of Medication Nonadherence to Co-medication Compared to Immunosuppressants in Heart Transplant Recipients: Findings From the International Cross-sectional BRIGHT Study

Abstract : Purpose: To assess and compare the prevalence of medication nonadherence (MNA) (implementation and persistence) to immunosuppressants and co-medications in heart transplant recipients. Methods: MNA prevalence was assessed using the Basel Assessment of Adherence to Immunosuppressive Medications Scale (self-report) and compared using logistic regression in a 4-continent sample of 1397 heart transplant recipients from 36 heart transplant centers in 11 countries. Findings: MNA was significantly (alpha = 0.05) higher to co-medications than to immunosuppressants (taking nonadherence: 23.9% vs 17.3%; odds ratio [OR] = 1.5; 95% CI, 1.30-1.73; drug holiday: 5.7% vs 1.9%; OR = 3.17; 95% CI, 2.13-4.73; dose alteration: 3.8% vs 1.6%; OR = 2.46; 95% CI, 1.49-4.06; and discontinuation: 2.6% vs 0.5%; OR = 5.15; 95% CI, 2.36-11.20). (C) 2018 Elsevier Inc. All rights reserved.
Document type :
Journal articles
Complete list of metadata

https://hal.archives-ouvertes.fr/hal-02466558
Contributor : Laboratoire Carmen Connect in order to contact the contributor
Submitted on : Tuesday, February 4, 2020 - 3:07:23 PM
Last modification on : Saturday, May 21, 2022 - 3:58:26 AM

Links full text

Identifiers

Citation

R. Helmy, K. Denhaerynck, L. Berben, F. Dobbels, C. L. Russell, et al.. Prevalence of Medication Nonadherence to Co-medication Compared to Immunosuppressants in Heart Transplant Recipients: Findings From the International Cross-sectional BRIGHT Study. Clin. Ther., 2019, 41 (1), pp.130--136. ⟨10.1016/j.clinthera.2018.11.007⟩. ⟨hal-02466558⟩

Share

Metrics

Record views

28