Integrating glycomics and genomics uncovers SLC10A7 as essential factor for bone mineralization by regulating post-Golgi protein transport and glycosylation

Angel Ashikov , Nurulamin Abu Bakar , Xiao-Yan Wen (1) , Marco Niemeijer , Glentino Rodrigues Pinto Osorio , Koroboshka Brand-Arzamendi , Linda Hasadsri , Hana Hansikova (2) , Kimiyo Raymond , Dorothée Vicogne (3, 4) , Nina Ondruskova , Marleen Simon (5) , Rolph Pfundt (6) , Sharita Timal , Roel Beumers , Christophe Biot (4) , Roel Smeets , Marjan Kersten , Karin Huijben , Peter Linders , Geert van den Bogaart , Sacha van Hijum , Richard Rodenburg (7) , Lambertus van den Heuvel , Francjan van Spronsen (8) , Tomas Honzik (2) , Francois Foulquier (4) , Monique van Scherpenzeel , Dirk Lefeber , Wamelink Mirjam , Brunner Han , Mundy Helen , Michelakakis Helen , van Hasselt Peter , van de Kamp Jiddeke , Martinelli Diego , Morkrid Lars , Brocke Holmefjord Katja , Hertecant Jozef , Alfadhel Majid , Carpenter Kevin , Te Water Naude Johann

1 Department of Medicine & Physiology , University of Toronto
2 1. LF UK / 1st Faculty of Medicine - 1. lékařská fakulta, Univerzita Karlova [Praha, Česká republika] = First Faculty of Medicine, Charles University [Prague, Czech Republic]
3 Université Lille Nord de France (COMUE)
4 UGSF - Unité de Glycobiologie Structurale et Fonctionnelle - UMR 8576
5 University Medical Center [Utrecht]
6 Department of Human Genetics
7 Paediatrics
8 Beatrix Children's Hospital/University Medical Center Groningen

Domaines: Sciences du Vivant [q-bio]; Biochimie, Biologie Moléculaire; Biochimie [q-bio.BM]

Angel Ashikov, Nurulamin Abu Bakar, Xiao-Yan Wen, Marco Niemeijer, Glentino Rodrigues Pinto Osorio, et al.. Integrating glycomics and genomics uncovers SLC10A7 as essential factor for bone mineralization by regulating post-Golgi protein transport and glycosylation. Human Molecular Genetics, 2018, 27 (17), pp.3029-3045. ⟨10.1093/hmg/ddy213⟩. ⟨hal-02399453⟩