PARP-1 protects against colorectal tumor induction, but promotes inflammation-driven colorectal tumor progression

Bastian Dörsam , Nina Seiwert (1) , Sebastian Foersch , Svenja Stroh (1) , Georg Nagel , Diana Begaliew , Erika Diehl , Alexander Kraus , Maureen Mckeague , Vera Minneker , Vassilis Roukos , Sonja Reissig , Ari Waisman (2) , Markus Moehler (3) , Anna Stier , Aswin Mangerich , Françoise Dantzer (4) , Bernd Kaina (1) , Jörg Fahrer (1)

1 Department of Toxicology
2 Department of Internal Medicine
3 Abteilung Innere I
4 IGBMC - Institut de Génétique et de Biologie Moléculaire et Cellulaire

Domaines: Sciences du Vivant [q-bio]

Bastian Dörsam, Nina Seiwert, Sebastian Foersch, Svenja Stroh, Georg Nagel, et al.. PARP-1 protects against colorectal tumor induction, but promotes inflammation-driven colorectal tumor progression. Proceedings of the National Academy of Sciences of the United States of America, 2018, 115 (17), pp.E4061-E4070. ⟨10.1073/pnas.1712345115⟩. ⟨hal-02369068⟩