Rivaroxaban compared with standard anticoagulants for the treatment of acute venous thromboembolism in children: a randomised, controlled, phase 3 trial

Christoph Male 1 Anthonie Lensing Joseph Palumbo Riten Kumar Ildar Nurmeev Kerry Hege Damien Bonnet 2 Philip Connor Hélène Hooimeijer Marcela Torres Anthony Chan Gili Kenet Susanne Holzhauer Amparo Santamaría Pascal Amedro 3, 4 Elizabeth Chalmers Paolo Simioni Rukhmi Bhat Donald Yee Olga Lvova Jan Beyer-Westendorf 5 Tina Biss Ida Martinelli Paola Saracco Marjolein Peters 6 Krisztián Kállay Cynthia Gauger M Patricia Massicotte Guy Young Akos Pap Madhurima Majumder William Smith Jürgen Heubach Scott Berkowitz Kirstin Thelen Dagmar Kubitza Mark Crowther 7 Martin Prins Paul Monagle Angelo Molinari Ulrike Nowak Göttl Juan Chain Jeremy Robertson Katharina Thom Werner Streif Rudolf Schwarz Klaus Schmitt Gernot Grangl An van Damme 8 Philip Maes 9 Veerle Labarque Antonio Petrilli Sandra Loggeto Estela Azeka Leonardo Brandao Doan Le 10 Christine Sabapathy Paola Giordano Runhui Wu Jie Ding Wenyan Huang Jianhua Mao Päivi Lähteenmäki Stéphane Decramer 11 Toralf Bernig Martin Chada Godfrey Chan Krisztian Kally Beatrice Nolan Shoshana Revel-Vilk 12 Hannah Tamary 13 Carina Levin Daniela Tormene Maria Abbattista Andrea Artoni Takanari Ikeyama Ryo Inuzuka Satoshi Yasukochi Michelle Morales Soto Karina Solis Labastida Monique Suijker Marike Bartels Rienk Tamminga C Heleen van Ommen D. Maroeska Te Loo Rui Anjos 14 Lyudmila Zubarovskaya Natalia Popova Elena Samochatova Margarita Belogurova Pavel Svirin Tatiana Shutova Vladimir Lebedev 15 Olga Barbarash Pei Koh Joyce Mei Ludmila Podracka Rubén Berrueco 16 Maria Fernandez 17 Tony Frisk Sebastian Grunt Johannes Rischewski Manuela Albisetti-Pedroni Ali Antmen Huseyin Tokgoz Zeynep Karakas Jayashree Motwani Michael Williams John Grainger Jeanette Payne Mike Richards 18 Susan Baird Neha Bhatnagar Angela Aramburo Shelley Crary Tung Wynn Shannon Carpenter Sanjay Ahuja Neil Goldenberg Gary Woods Kamar Godder Ajovi Scott-Emuakpor Gavin Roach Leslie Raffini Nirmish Shah Sanjay Shah Courtney Thornburg Ayesha Zia Roger Berkow
Abstract : Treatment of venous thromboembolism in children is based on data obtained in adults with little direct documentation of its efficacy and safety in children. The aim of our study was to compare the efficacy and safety of rivaroxaban versus standard anticoagulants in children with venous thromboembolism.
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Journal articles
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Submitted on : Sunday, November 10, 2019 - 5:52:28 PM
Last modification on : Monday, November 11, 2019 - 1:26:44 AM

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Christoph Male, Anthonie Lensing, Joseph Palumbo, Riten Kumar, Ildar Nurmeev, et al.. Rivaroxaban compared with standard anticoagulants for the treatment of acute venous thromboembolism in children: a randomised, controlled, phase 3 trial. The Lancet Haematology, Elsevier, 2019, ⟨10.1016/S2352-3026(19)30219-4⟩. ⟨hal-02357722⟩

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