New Formulation for the Delivery of Oligonucleotides Using “Clickable” siRNA-Polyisoprenoid-Conjugated Nanoparticles: Application to Cancers Harboring Fusion Oncogenes

Liliane Massaad-Massade (1) , Suzan Boutary , Marie Caillaud (2) , Céline Gracia (3) , Beatrice Parola , Soukaina Bel Gnaouiya , Barbara Stella , Silvia Arpicco , Eric Buchy , Didier Desmaele (4) , Patrick Couvreur (5) , Giorgia Urbinati (6)

1 U490 - Toxicologie Moleculaire
2 LPPA - Laboratoire de Physiologie de la Perception et de l'Action
3 Institut Gilbert-Laustriat : Biomolécules, Biotechnologie, Innovation Thérapeutique
4 IGPS - Institut Galien Paris-Sud
5 PCPB - Physico-chimie, pharmacotechnie, biopharmacie
6 UMR 8203 - Vectorologie et thérapeutiques anti-cancéreuses [Villejuif]

Domaines: Sciences pharmaceutiques

Liliane Massaad-Massade, Suzan Boutary, Marie Caillaud, Céline Gracia, Beatrice Parola, et al.. New Formulation for the Delivery of Oligonucleotides Using “Clickable” siRNA-Polyisoprenoid-Conjugated Nanoparticles: Application to Cancers Harboring Fusion Oncogenes. Bioconjugate Chemistry, 2018, 29 (6), pp.1961-1972. ⟨10.1021/acs.bioconjchem.8b00205⟩. ⟨hal-02349758⟩