Backbone cyclization of native α-conotoxin CIA dramatically increases affinity at neuronal nicotinic receptors

Julien Giribaldi (1) , David Wilson (2) , Yves Haufe , Rosanna Mary (1) , Edward Ewans , Nathalie Kurrle , Casey Schmidt , Norelle L Daly , Anna Krautloher , Adèle Faucherre (3) , Hamid Moha Ou Maati (3) , Pierre Charnet (1) , Christine Enjalbal (1) , Annette Nicke (4) , Sébastien Dutertre (1)

1 IBMM - Institut des Biomolécules Max Mousseron [Pôle Chimie Balard]
2 JCU - James Cook University
3 IGF - Institut de Génomique Fonctionnelle
4 LMU - Ludwig Maximilian University [Munich] = Ludwig Maximilians Universität München

Domaines: Biophysique

Julien Giribaldi, David Wilson, Yves Haufe, Rosanna Mary, Edward Ewans, et al.. Backbone cyclization of native α-conotoxin CIA dramatically increases affinity at neuronal nicotinic receptors. 25th Meeting of the French Society of Toxinology (SFET), Nov 2018, Paris, France. ⟨hal-02349001⟩