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[Demonstration of an inoculum effect on the estimation of the minimal inhibitory concentration of LY 146032].

Abstract : This work has been performed to study the inoculum effect on the in vitro activity of LY 146032, a new lipopeptide antibiotic. A statistical analysis (X2 and t test) of the data concerning the MIC of different bacterial groups has been carried out to appreciate the phenomenon. The activity of vancomycin has been compared. A major inoculum effect has been detected for LY 146032. It must be taken into account to evaluate the activity of this new antibiotic.
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https://hal.archives-ouvertes.fr/hal-02332666
Contributor : Jean-Pierre Flandrois Connect in order to contact the contributor
Submitted on : Thursday, October 24, 2019 - 10:20:32 PM
Last modification on : Wednesday, July 21, 2021 - 3:10:02 PM

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  • HAL Id : hal-02332666, version 1
  • PUBMED : 2841637

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Jean-Pierre Flandrois, G. Carret, M. Peyret, Catherine Pichat. [Demonstration of an inoculum effect on the estimation of the minimal inhibitory concentration of LY 146032].. Pathologie Biologie, Elsevier Masson, 1988, 36 (5), pp.377-80. ⟨hal-02332666⟩

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