High-flow Nasal Cannulae Versus Non-invasive Ventilation for Preoxygenation of Obese Patients: The PREOPTIPOP Randomized Trial

Mickael Vourc'H (1) , Gabrielle Baud (1) , Fanny Feuillet (2, 3) , Claire Blanchard (4) , Eric Mirallié (5, 6) , Christophe Guitton (7, 8) , Samir Jaber (9, 10) , Karim Asehnoune (1)

1 CHU Nantes - Centre Hospitalier Universitaire de Nantes
2 Biostatistique, Recherche Clinique et Mesures Subjectives en Santé
3 SPHERE - MethodS in Patients-centered outcomes and HEalth ResEarch
4 General and Digestive Surgery Department,
5 Clinique de chirurgie digestive et endocrinienne
6 General and Digestive Surgery Department,
7 Immunointervention dans les allo et xénotransplantations
8 Centre Hospitalier Le Mans (CH Le Mans)
9 PhyMedExp - Physiologie & médecine expérimentale du Cœur et des Muscles [U 1046]
10 CHRU Montpellier - Centre Hospitalier Régional Universitaire [Montpellier]

In obese patients, preoxygenation with non-invasive ventilation (NIV) was reported to improve outcomes compared with facemask. In this setting, high-flow nasal cannulae (HFNC) used before and during intubation has never been studied against NIV.

Mots clés: Apnoeic oxygenation; High-flow oxygen therapy by nasal cannulae; Intubation; Morbid obesity; Non-invasive ventilation; Preoxygenation

Domaines: Sciences du Vivant [q-bio]

Mickael Vourc'H, Gabrielle Baud, Fanny Feuillet, Claire Blanchard, Eric Mirallié, et al.. High-flow Nasal Cannulae Versus Non-invasive Ventilation for Preoxygenation of Obese Patients: The PREOPTIPOP Randomized Trial. EClinicalMedicine, 2019, 13, pp.112-119. ⟨10.1016/j.eclinm.2019.05.014⟩. ⟨hal-02291780⟩