Cues predicting drug or food reward restore morphine-induced place conditioning in mice lacking delta opioid receptors

Abstract : The exact role of delta opioid receptors in drug-induced conditioned place preference (CPP) remains debated. Under classical experimental conditions, morphine-induced CPP is decreased in mice lacking delta opioid receptors (Oprd1 (-/-)). Morphine self-administration, however, is maintained, suggesting that drug-context association rather than drug reward is deficient in these animals.
Complete list of metadatas

https://hal.archives-ouvertes.fr/hal-02266441
Contributor : Julie Le Merrer <>
Submitted on : Wednesday, August 14, 2019 - 2:08:59 PM
Last modification on : Thursday, August 15, 2019 - 1:19:09 AM

Links full text

Identifiers

Collections

Citation

Julie Le Merrer, Lauren Faget, Audrey Matifas, Brigitte Kieffer. Cues predicting drug or food reward restore morphine-induced place conditioning in mice lacking delta opioid receptors. Psychopharmacology, Springer Verlag, 2012, 223 (1), pp.99-106. ⟨10.1007/s00213-012-2693-1⟩. ⟨hal-02266441⟩

Share

Metrics

Record views

9