Insulin-like growth factor induces the survival and proliferation of myeloma cells through an interleukin-6-independent transduction pathway

M. Ferlin , N. Noraz , C. Hertogh , J. Brochier , N. Taylor (1) , B. Klein

1 IGMM - Institut de Génétique Moléculaire de Montpellier

Mots clés: Apoptosis Blotting; Chemical Trans-Activators/metabolism; Western Cell Division/drug effects Cell Line DNA/biosynthesis DNA-Binding Proteins/metabolism Flow Cytometry Humans Insulin-Like Growth Factor I/*pharmacology Interleukin-6/*immunology MAP Kinase Signaling System/drug effects Multiple Myeloma/*immunology Phosphoproteins/metabolism Precipitin Tests STAT3 Transcription Factor Signal Transduction/*drug effects Stimulation

Domaines: Biochimie, Biologie Moléculaire

M. Ferlin, N. Noraz, C. Hertogh, J. Brochier, N. Taylor, et al.. Insulin-like growth factor induces the survival and proliferation of myeloma cells through an interleukin-6-independent transduction pathway. British Journal of Haematology, 2000, 111 (2), pp.626--34. ⟨10.1046/j.1365-2141.2000.02364.x⟩. ⟨hal-02196817⟩