LYL1 activity is required for the maturation of newly formed blood vessels in adulthood

N. Pirot , Virginie Deleuze (1) , R. El-Hajj , C. Dohet , F. Sablitzky , P. Couttet , D. Mathieu , V. Pinet

1 IGMM - Institut de Génétique Moléculaire de Montpellier

Mots clés: Neoplastic/genetics Hematopoiesis/genetics Humans Mice Mice; Pathologic/genetics/*metabolism Proto-Oncogene Proteins/genetics/metabolism Up-Regulation/genetics; Mutant Strains Neoplasm Proteins/genetics/*metabolism Neoplasm Transplantation Neoplasms; Experimental/*blood supply/genetics/*metabolism Neovascularization; CD/biosynthesis/genetics Basic Helix-Loop-Helix Transcription Factors/genetics/*metabolism Cadherins/biosynthesis/genetics Gene Expression Regulation; Angiopoietin-2/biosynthesis/genetics Animals Antigens

Domaines: Biochimie, Biologie Moléculaire

N. Pirot, Virginie Deleuze, R. El-Hajj, C. Dohet, F. Sablitzky, et al.. LYL1 activity is required for the maturation of newly formed blood vessels in adulthood. Blood, 2010, 115 (25), pp.5270--9. ⟨10.1182/blood-2010-03-275651⟩. ⟨hal-02193618⟩