3-Amino-3,4-dihydro-2 H -1-benzopyran Derivatives as 5-HT 1A Receptor Ligands and Potential Anxiolytic Agents. 2. Synthesis and Quantitative Structure−Activity Relationship Studies of Spiro[pyrrolidine- and piperidine-2,3‘(2‘ H )-benzopyrans] †

Corinne Comoy (1) , Christophe Marot (1) , Tchao Podona (1) , Marie-Laure Baudin (1) , Luc Morin-Allory (1) , Gérald Guillaumet (1) , Bruno Pfeiffer (2) , Daniel-Henry Caignard (2) , Pierre Renard (2) , Marie-Claire Rettori , Gérard Adam (2) , Beatrice Guardiola-Lemaitre

1 ICOA - Institut de Chimie Organique et Analytique
2 ADIR-Servier Research Group

Domaines: Chimie organique

Corinne Comoy, Christophe Marot, Tchao Podona, Marie-Laure Baudin, Luc Morin-Allory, et al.. 3-Amino-3,4-dihydro-2 H -1-benzopyran Derivatives as 5-HT 1A Receptor Ligands and Potential Anxiolytic Agents. 2. Synthesis and Quantitative Structure−Activity Relationship Studies of Spiro[pyrrolidine- and piperidine-2,3‘(2‘ H )-benzopyrans] †. Journal of Medicinal Chemistry, 1996, 39 (21), pp.4285-4298. ⟨10.1021/jm950861w⟩. ⟨hal-02187050⟩