First description of Mycobacterium tuberculosis and M. canettii concomitant infection: report of two cases

N. Paleiron (1, 2) , C. Soler (3) , M. O. Hassan , D. Andriamanantena (4) , R. Vong , Christine Pourcel (5, 6) , J.-B. Roseau

1 GETBO - Groupe d'Etude de la Thrombose de Bretagne Occidentale
2 CIC Brest
3 Hôpital d'instruction des Armées Percy
4 Service des Maladies Infectieuses et Tropicales [Hôpital d’Instruction des Armées Bégin]
5 I2BC - Institut de Biologie Intégrative de la Cellule
6 SSFA - Séquence, Structure et Fonction des ARN

\textlessh2\textgreaterSUMMARY\textless/h2\textgreaterWe report the first two cases of tuberculous coinfection with Mycobacterium tuberculosis and M. canettii. Both patients were young Djiboutian females with pulmonary tuberculosis (TB). One had a miliary pattern with concomitant human immunodeficiency virus infection. Both recovered completely with a standard four-drug anti-tuberculosis treatment regimen. Due to the different natural reservoirs and routes of infection of these two strains, our study supports the common belief that multiple strains of infection in TB are related to superinfection rather than concomitant infection.

Mots clés: tuberculosis; coinfection; Mycobacterium canettii

Domaines: Sciences du Vivant [q-bio]

N. Paleiron, C. Soler, M. O. Hassan, D. Andriamanantena, R. Vong, et al.. First description of Mycobacterium tuberculosis and M. canettii concomitant infection: report of two cases. International Journal of Tuberculosis and Lung Disease, 2019, 23 (2), pp.232--+. ⟨10.5588/ijtld.18.0261⟩. ⟨hal-02173635⟩