Z-DNA as a probe for localized supercoiling in vivo

Abstract : Biological processes such as transcription are expected to generate local variations in DNA supercoiling. The existence of localized supercoiling was recently demonstrated in Escherichia coli by using the supercoil-driven B-to-Z transition as a superhelicity probe. This new methodology is described and its extension to other biological systems discussed.
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https://hal.archives-ouvertes.fr/hal-02127207
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Submitted on : Monday, May 13, 2019 - 11:55:37 AM
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A. Rachid Rahmouni. Z-DNA as a probe for localized supercoiling in vivo. Molecular Microbiology, Wiley, 1992, 6 (5), pp.569-572. ⟨10.1111/j.1365-2958.1992.tb01502.x⟩. ⟨hal-02127207⟩

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