A genomic history of Aboriginal Australia

Anna-Sapfo Malaspinas Michael Westaway Craig Muller Vitor Sousa 1 Oscar Lao 2 Isabel Alves Anders Bergström 3 Georgios Athanasiadis Jade Cheng Jacob Crawford Tim Heupink Enrico Macholdt 4 Stephan Peischl Rasmus Rasmussen Stephan Schiffels Sankar Subramanian 5 Joanne Wright Anders Albrechtsen 6 Chiara Barbieri Isabelle Dupanloup 7 Anders Eriksson 8 Ashot Margaryan Ida Moltke Irina Pugach Thorfinn Korneliussen Ivan Levkivskyi J Víctor Moreno-Mayar Shengyu Ni Fernando Racimo Martin Sikora 9 Yali Xue 10 Jeffrey Aghakhanian Nicolas Brucato 11 Søren Brunak 12 Paula Campos Warren Wales Sturla Ellingvåg Gudjugudju Fourmile Pascale Gerbault Darren Injie George Koki Matthew Leavesley Betty Logan Aubrey Lynch Elizabeth Matisoo-Smith 13 Peter Mcallister 14 Alexander Mentzer 15 Mait Metspalu 16 Andrea Migliano Les Murgha Jeffrey Phipps William Pomat Doc Reynolds Francois-Xavier Ricaut 11 Peter Siba 17 Mark Thomas Thomas Wales Colleen Ma'Run Wall Stephen Oppenheimer Chris Tyler-Smith 18 Richard Durbin 19 Joe Dortch Andrea Manica Mikkel Schierup Robert Foley Marta Mirazón Lahr Claire Bowern 20 Jeffrey Wall Thomas Mailund 21 Mark Stoneking 4 Rasmus Nielsen 22 Manjinder Sandhu 23 Laurent Excoffier 24 David Lambert 25 Eske Willerslev 26 Simon Rasmussen 27 Isabel Dupanloup J. Víctor Moreno-Mayar Farhang Aghakhanian Nicolas Ni Warren Clark Maude Phipps Colleen Ma’run Wall Thomas Thomas Rasmus Ni
Abstract : The population history of Aboriginal Australians remains largely uncharacterized. Here we generate high-coverage genomes for 83 Aboriginal Australians (speakers of Pama-Nyungan languages) and 25 Papuans from the New Guinea Highlands. We find that Papuan and Aboriginal Australian ancestors diversified 25-40 thousand years ago (kya), suggesting pre-Holocene population structure in the ancient continent of Sahul (Australia, New Guinea and Tasmania). However, all of the studied Aboriginal Australians descend from a single founding population that differentiated ~10-32 kya. We infer a population expansion in northeast Australia during the Holocene epoch (past 10,000 years) associated with limited gene flow from this region to the rest of Australia, consistent with the spread of the Pama-Nyungan languages. We estimate that Aboriginal Australians and Papuans diverged from Eurasians 51-72 kya, following a single out-of-Africa dispersal, and subsequently admixed with archaic populations. Finally, we report evidence of selection in Aboriginal Australians potentially associated with living in the desert.
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Anna-Sapfo Malaspinas, Michael Westaway, Craig Muller, Vitor Sousa, Oscar Lao, et al.. A genomic history of Aboriginal Australia. Nature, Nature Publishing Group, 2016, 538 (7624), pp.207-214. ⟨10.1038/nature18299⟩. ⟨hal-02112765⟩



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