Mutations in NONO lead to syndromic intellectual disability and inhibitory synaptic defects

Dennis Mircsof , Maéva Langouët Langouët (1, 2, 3, 4) , Marlène Rio (5, 1, 2, 3) , Sébastien Moutton (4, 1, 2, 3) , Karine Siquier-Pernet (1, 4, 2, 3) , Christine Bole-Feysot (1, 4, 2, 3, 6) , Nicolas Cagnard (7, 1, 2, 3, 4) , Patrick Nitschke (1, 7, 2, 3, 4) , Ludmila Gaspar , Matej Žnidarič , Olivier Alibeu (1, 6, 2, 3, 4) , Ann-Kristina Fritz , David Wolfer (8) , Aileen Schröter , Giovanna Bosshard , Markus Rudin , Christina Koester , Florence Crestani , Petra Seebeck , Nathalie Boddaert (1, 2, 3, 4, 9, 10) , Katrina Prescott (11) , Rochelle Hines , Steven Moss , Jean-Marc Fritschy (12) , Arnold Munnich (1, 2, 3) , Jeanne Amiel (1, 2, 3, 5, 10) , Steven Brown , Shiva Tyagarajan , Laurence Colleaux (1, 2, 3, 4)

1 IMAGINE - U1163 - Imagine - Institut des maladies génétiques
2 UPD5 - Université Paris Descartes - Paris 5
3 USPC - Université Sorbonne Paris Cité
4 Hôpital Necker - Enfants Malades [AP-HP]
5 Service de Génétique Médicale [CHU Necker]
6 Plateforme de génomique [SFR Necker]
7 BIP-D - Plateforme Bioinformatique [SFR Necker]
8 Institute of Anatomy
9 Service de radiologie pédiatrique [CHU Necker]
10 AP-HP - Assistance publique - Hôpitaux de Paris (AP-HP)
11 Department of Clnical Genetics, Chapel Allerton Hospital
12 Institute of Pharmacology and Toxicology [Zurich]

Domains: Human genetics

Dennis Mircsof, Maéva Langouët Langouët, Marlène Rio, Sébastien Moutton, Karine Siquier-Pernet, et al.. Mutations in NONO lead to syndromic intellectual disability and inhibitory synaptic defects. Nature Neuroscience, 2015, 18 (12), pp.1731-1736. ⟨10.1038/nn.4169⟩. ⟨hal-02088168⟩