Design and validation of a homogeneous time-resolved fluorescence cell-based assay targeting the ligand-gated ion channel 5-HT3A

Emilie Blanc (1) , Patrick Wagner (2) , Fabrice Plaisier (3) , M. Schmitt (2) , Thierry Durroux (1) , J. J. Bourguignon (2) , M. Partiseti (3) , E. Dupuis , F. Bihel (2)

1 IGF - Institut de Génomique Fonctionnelle
2 LIT - Laboratoire d'Innovation Thérapeutique
3 Sanofi-Aventis R&D

Domaines: Sciences du Vivant [q-bio]

Emilie Blanc, Patrick Wagner, Fabrice Plaisier, M. Schmitt, Thierry Durroux, et al.. Design and validation of a homogeneous time-resolved fluorescence cell-based assay targeting the ligand-gated ion channel 5-HT3A. Analytical Biochemistry, 2015, 484, pp.105-12. ⟨10.1016/j.ab.2015.03.035⟩. ⟨hal-02064366⟩