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Benefit of a new provisional stenting strategy, the re-proximal optimisation technique: the rePOT clinical study

Abstract : Aims: A new coronary bifurcation provisional stenting technique without kissing balloon, rePOT, associating the proximal optimisation technique (POT), side branch inflation and final POT, showed excellent mechanical results in a bench test. The present study sought to use optical coherence tomography (OCT) to quantify the mechanical results of rePOT in vivo in a large patient sample with complex coronary bifurcations. Methods and results: A total of 106 patients with coronary bifurcations were included in a multicentre prospective registry (left main, 40.6%; true Medina bifurcation, 39.6%). Three OCT runs were performed, at baseline, just after stent implantation and after the complete rePOT sequence, quantifying global malapposition, side branch obstruction (SBO), and various geometric arterial criteria. RePOT was completed systematically. RePOT significantly reduced global strut malapposition from 18.9 +/- 13.4% just after stent implantation to 3.2 +/- 3.9% (p\textless0.05), residual SBO from 44.3 +/- 12.9% to 17.0 +/- 14.3% (p\textless0.05), and ellipticity index from 1.19 +/- 0.11 to 1.13 +/- 0.12 (p\textless0.05). Exhaustive six-month follow-up found only one mother-vessel target lesion revascularisation. Conclusions: This clinical study of a large sample of complex coronary bifurcations with OCT analysis showed the benefit of the rePOT sequence in provisional stenting, replicating in vivo the excellent in vitro geometric results previously reported, and confirming ease of implementation and medium-term safety.
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https://hal.archives-ouvertes.fr/hal-02003822
Contributor : Laboratoire Carmen <>
Submitted on : Friday, February 1, 2019 - 1:56:31 PM
Last modification on : Wednesday, February 24, 2021 - 4:16:02 PM

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  • HAL Id : hal-02003822, version 1

Citation

F. Derimay, Gerard Finet, G. Souteyrand, L. Maillard, A. Aminian, et al.. Benefit of a new provisional stenting strategy, the re-proximal optimisation technique: the rePOT clinical study. EuroIntervention , EuroPCR, 2018, 14 (3), pp.325--332. ⟨hal-02003822⟩

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