Subtelomere organization in the genome of the microsporidian Encephalitozoon cuniculi: patterns of repeated sequences and physicochemical signatures

Abstract : The microsporidian Encephalitozoon cuniculi is an obligate intracellular eukaryotic pathogen with a small nuclear genome (2.9 Mbp) consisting of 11 chromosomes. Although each chromosome end is known to contain a single rDNA unit, the incomplete assembly of subtelomeric regions following sequencing of the genome identified only 3 of the 22 expected rDNA units. While chromosome end assembly remains a difficult process in most eukaryotic genomes, it is of significant importance for pathogens because these regions encode factors important for virulence and host evasion.
Liste complète des métadonnées

https://hal.archives-ouvertes.fr/hal-01983985
Contributeur : Genevieve Bricheux <>
Soumis le : lundi 28 janvier 2019 - 10:12:39
Dernière modification le : jeudi 7 février 2019 - 15:11:52

Fichier

Dia_2016_BMC_genomics.pdf
Publication financée par une institution

Licence


Distributed under a Creative Commons Paternité 4.0 International License

Identifiants

Citation

Ndongo Dia, Laurence Lavie, Ngor Faye, Guy Méténier, Edouard Yeramian, et al.. Subtelomere organization in the genome of the microsporidian Encephalitozoon cuniculi: patterns of repeated sequences and physicochemical signatures. BMC Genomics, BioMed Central, 2016, 17 (1), pp.34. 〈10.1186/s12864-015-1920-7〉. 〈hal-01983985〉

Partager

Métriques

Consultations de la notice

83

Téléchargements de fichiers

8