Ochratoxin A Dietary Exposure of Ten Population Groups in the Czech Republic: Comparison with Data over the World

Vladimir Ostry (1) , Frantisek Malir (2) , Marcela Dofkova (1) , Jarmila Skarkova (1) , Annie Pfohl-Leszkowicz (3) , Jiri Ruprich (1)

1 National Institute of Public Health [Prague]
2 University of Hradec Králové
3 LGC - Laboratoire de Génie Chimique

Ochratoxin A is a nephrotoxic and renal carcinogenic mycotoxin and is a common contaminant of various food commodities. Eighty six kinds of foodstuffs (1032 food samples) were collected in 2011–2013. High-performance liquid chromatography with fluorescence detection was used for ochratoxin A determination. Limit of quantification of the method varied between 0.01–0.2 μg/kg depending on the food matrices. The most exposed population is children aged 4–6 years old. Globally for this group, the maximum ochratoxin A dietary exposure for “average consumer” was estimated at 3.3 ng/kg bw/day (lower bound, considering the analytical values below the limit of quantification as 0) and 3.9 ng/kg bw/day (middle bound, considering the analytical values below the limit of quantification as 1/2 limit of quantification). Important sources of exposure for this latter group include grain-based products, confectionery, meat products and fruit juice. The dietary intake for “high consumers” in the group 4–6 years old was estimated from grains and grain-based products at 19.8 ng/kg bw/day (middle bound), from tea at 12.0 ng/kg bw/day (middle bound) and from confectionery at 6.5 ng/kg bw/day (middle bound). For men aged 18–59 years old beer was the main contributor with an intake of 2.60 ng/kg bw/day (“high consumers”, middle bound). Tea and grain-based products were identified to be the main contributors for dietary exposure in women aged 18–59 years old. Coffee and wine were identified as a higher contributor of the OTA intake in the population group of women aged 18–59 years old compared to the other population groups

Mots clés: Ochratoxin A; Food; Exposure sources; Dietary exposure; Czech population

Domaines: Génie chimique; Génie des procédés

Vladimir Ostry, Frantisek Malir, Marcela Dofkova, Jarmila Skarkova, Annie Pfohl-Leszkowicz, et al.. Ochratoxin A Dietary Exposure of Ten Population Groups in the Czech Republic: Comparison with Data over the World. Toxins, 2015, 7 (9), pp.3608-3635. ⟨10.3390/toxins7093608⟩. ⟨hal-01894484⟩